Nuclear Medicine at 154 Harley Street

Two state of the art gamma cameras are now available at 154 Harley Street. The SPECT/CT provides true 3D information and improves diagnostic sensitivity. The introduction of this technique enables physicians to even more accurately localise areas of increased tracer uptake by overlying the functional SPECT images with the detailed anatomical images of a CT scan.

The Main clinical areas to benefit from SPECT/CT are:

  • Bone/Orthopaedic Imaging: Lower back pain-facet joint assessment /Joint Prosthesis assessment /Bone and Joint infections / Occult fractures etc)
  • Tumour Imaging: bone metastases / Tumour receptor imaging with MIBG and Octreotide Scans/ Thyroid Cancer
  • Parathyroid localisation and other endocrine tumours: SPECT-CT permits accurate localisation, clarity and precision.

Nuclear Medicine Applications

Cardiac nuclear medicine studies provide pictures of the structure and function of the heart. They help visualize blood flow patterns to the heart wall muscles and are used to help diagnose cardiac disease such as unexplained chest pain or chest pain brought on by exercise.

Examples of Cardiac Applications:
Coronary Artery Disease
Measure Effectiveness of Bypass Surgery
Select Patients for Bypass or Angioplasty
Measure Chemotherapy Cardiac Toxicity
  Diagnostic Studies performed:
Myocardial Perfusion Imaging

Progress in nuclear medicine has always been a function of technological advances, and applications in neurology and psychiatry illustrate the point. Improvements in radiation detectors now allow for three-dimensional and quantitative mapping of the distribution of a labelled compound in the human brain.

Neurologic Applications:
123I DaTSCAN is an invaluable imaging test to enable differentiation between both Parkinsonian syndromes/ essential tremor and Alzheimer’s disease/ probable dementia with Lewy bodies. The diagnostic accuracy of this test enables an early accurate diagnosis facilitating optimal patient management.

The role of nuclear medicine in the diagnosis and management of malignant disease is constantly evolving. Advances in chemotherapy necessitate careful monitoring of the effects of chemotherapeutic drugs on normal organ function during follow-up, and tumour specific radiopharmaceuticals are being used for non-invasive, targeted tumour therapy.

Radionuclide investigations play an important role in several aspects of follow-up in oncology patients. They may be used to determine adequacy of surgery or other primary therapy.

We also offer therapeutic procedures such as radioactive iodine (I-131) therapy that uses radioactive material to treat cancer and other medical conditions affecting the thyroid gland.

Oncologic Applications:
Tumor Localization
Tumor Staging
Identify Metastatic Sites
Assess Response to Therapy
Relieve Bone Pain Caused by Cancer
Thyroid tissue deactivation/ ablation

Treatment Tests Performed:
131 Iodine- Thyroid Cancer Treatment/ Thyrotoxicosis
131 I-MIBG – For neuroblastoma and phaeochromocytoma
  Diagnostic Studies Performed:
Bone Scan
- GFR/ EDTA Test
Octreotide Study
MIBG Study
- Thyroid imaging

Nuclear Medicine renal scintigraphy provides important functional data for the diagnosis and management of patients with a variety of suspected genitourinary problems.

A major area of renal scintigraphy is in the evaluation of obstructive uropathy with the introduction of diuretic renography. Imaging is also of proven value in trauma, renovascular hypertension, and acute and chronic renal failure.

Renal Applications:
Detect Urinary Tract Obstruction
Detect Reflux after Urinary Tract Infection
Diagnose Renovascular Hypertension
Measure Differential Renal Function
Detect Renal Transplant Rejection
Detect Pyelonephritis
Detect Renal Scars
  Diagnostic Studies Performed:
Renal Cortical Scintigraphy (DMSA)
Renogram +/- Diuretic (MAG3)
Indirect Radionuclide Cystography
Measurement of Glomerular Filtration Rate (GFR)

Nearly all Nuclear Medicine procedures can also be performed on paediatric patients. If the radiotracer is given intravenously, the child may feel a slight pin-prick when the needle is inserted into the vein. It is also important that the child remains very still while the images are being recorded. Parents are encouraged to stay with their children to help them remain calm and still during imaging. Comfort items such as pacifiers, blankets and books are also very helpful. A television with children's programming is available in the scanning rooms.

Paediatric Applications:
Urinary blockage in the kidney
Backflow of urine from the bladder into the kidney
Bone cancer, infections and trauma
Gastrointestinal bleeding
Tumours and the spread of cancerous cells in the body
Jaundice in newborns and older children
  Diagnostic Studies Performed:
MAG3 Renogram +/- Micturating Cystogram
DMSA scan

Bone Scan
Octreotide Study
- MIBG Study
Meckels Diverticulum Study
GI Bleed studies
Gastric Emptying


We are also one of the only private clinics to offer SeHCAT testing. This simple but accurate test can help clinicians diagnose bile salt malabsorption, a common cause of chronic diarrhoea. This condition can then be simply treated, without the need for any further tests and the patient regains their quality of life.

So how can you refer patients for Nuclear Medicine Studies?

Complete the Referral Form (download here), detailing the type of test you require. You can also call us on 020 7725 6800 if you would like us to send you a copy.

Fax to 020 7725 6868 or post to the address below
Any queries please telephone us on 020 7725 6800
Opening Times Monday – Friday 08:30 – 17:30

The Harley Street Clinic Molecular Imaging Centre,
154 Harley Street, London, W1G 7LJ